中风病人急性期、慢性早期的BOLD-fMRI对比研究

目的：探索脑中风后运动相关脑区激活的变化情况。方法：分析16例经临床和影像确诊的中风患者急性期和慢性早期的激活表现。结果：患手食指被动运动时主要激活对侧SM1区，其它非SM1区有时可见散在、微弱激活；纵向比较16例患者各运动相关脑区的激活体积、频率，其差异均无统计学意义（P＞0.05），前后肌力差异亦无统计学意义（P＞0.05）；康复较好的患者，纵向比较肌力有升高（P＜0.05），对侧SM1区的激活体积增大（P＞0.05）；对侧SM1区变化可有3种形式：激活体积增大、前后无变化及激活体积减小。结论：fMRI是一种有效的研究脑功能变化的成像方法。对侧SM1区是一个重要的运动脑区，其激活变化可以多样化。

A comparative study of BOLD-fMRI between acute stage and early chronic stage of cerebral infarct

Objective: To investigate the cortical activation changes after stroke. Materials and Methods: BOLD-fMRI findings in 16 patients with cerebral infarction confirmed by clinical and imaging materials were analyzed. Results: The activation of patients were mainly located in the contralateral SM1 and occasionally scattered in the non-SM1 cortex. There was no statistical significance in activation volumes, activation frequencies of cortex relative to movement by longitudinal comparison between acute stage and ea...