NITRIC OXIDE IS NOT INCREASED IN ALCOHOLIC BRAIN |
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Authors: | NEIMAN, JACK BENTHIN, GUNTHER |
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Affiliation: | Department of Clinical Neuroscience, Karolinska Institute, Clinical Alcohol and Drug Addiction Research Section Stockholm, Sweden 1Department of Clinical Physiology, Karolinska Institutet at Huddinge University Hospital Huddinge, Sweden and Finnigan MAT AB, 141 75 Huddinge, Sweden |
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Abstract: | Nitric oxide (NO) metabolites nitrite and nitrate were measuredin the cerebrospinal fluid in 12 alcohol-dependent subjectsand in 16 healthy controls. The amounts of NO metabolites inalcoholics were not different from those in the controls. Theresults suggest that NO is not a major factor responsible forbrain damage in these patients. |
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