复方玄驹胶囊联合盐酸阿朴吗啡治疗勃起功能障碍的临床研究

目的:观察复方玄驹胶囊联合盐酸阿朴吗啡治疗阴茎勃起功能障碍(ED)的疗效。方法:采用复方玄驹胶囊联合盐酸阿朴吗啡治疗115例ED患者为治疗组,单用盐酸阿朴吗啡治疗111例作为对照组,经连续2个月的治疗后,观察两组的国际勃起功能问卷(IIEF-5)的评分改变情况。结果:治疗组与对照组IIEF-5的评分在治疗前分别为(11.42±2.38)、(11.56±2.65)分,两组比较差异无显著性(P>0.05);治疗后分别为(17.85±2.68)、(13.96±3.25)分,均有明显提高(P<0.01),而治疗组在治疗后的评分明显高于对照组(P<0.01);治疗组的显效率、有效率和总有效率均高于对照组。结论:复方玄驹胶囊联合盐酸阿朴吗啡治疗ED有较好疗效,值得临床推广使用。

Efficacy of Compound Xuanju Capsule combined with apomorphine hydrochloride on erectile dysfunction

Objective: To investigate the clinical effect of Compound Xuanju Capsule combined with apomorphine hydrochloride on penile erectile dysfunction(ED).Methods: We treated 115 ED patients with Compound Xuanju Capsule plus apomorphine hydrochlorid(trial group),and another 111 with apomorphine hydrochloride alone(control group),both for two months.Then we compared the IIEF-5 scores between the two groups.Results: After treatment,the IIEF-5 scores were 17.85±2.68 and 13.96±3.25 in the trial and control group,respectively,significantly higher than 11.42±2.68 and 13.96±3.25 before treatment(P<0.01).There were statistically significant differences between the two groups either in post-treatment IIEF-5 scores(P<0.01) or in the rates of obvious effectiveness,effectiveness and total effectiveness.Conclusion: Compound Xuanju Capsule combined with apomorphine hydrochloride has a good curative effect on ED,and deserves general clinical application.