| 二氢埃托啡成瘾者的甲状腺功能、胰腺分泌及睾酮变化 |
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| 引用本文： | 王志纲,赵金栓,赵竹林,韩艳秋,杨毓章,富景春,李秀莲,张宪武. 二氢埃托啡成瘾者的甲状腺功能、胰腺分泌及睾酮变化[J]. 中国新药与临床杂志, 1996, 0(6) |
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| 作者姓名： | 王志纲 赵金栓 赵竹林 韩艳秋 杨毓章 富景春 李秀莲 张宪武 |
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| 作者单位： | 内蒙古精神卫生中心，内蒙古医学院第一附属医院，内蒙古医学院药理教研室 |
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| 摘 要： | 目的：观察二氢埃托啡成瘾者的甲状腺功能、胰腺分泌及睾酮变化。方法：用放射免疫法测定１１例男性二氢埃托啡成瘾者与２９例男性海洛因成瘾者及２６例正常对照组血中ＴＳＨ，Ｔ３，Ｔ４，Ｃ肽，胰岛素及睾酮含量。结果：二氢埃托啡成瘾者与正常对照组比较，ＴＳＨ，Ｔ３下降显著（Ｐ＜０．０１）；Ｃ肽和胰岛素增加明显（Ｐ＜０．０１）；Ｔ４下降、睾酮升高，差别不显著（Ｐ＞０．０５）。二氢埃托啡组与海洛因组比较，Ｔ３下降不显著（Ｐ＞０．０５）；ＴＳＨ和Ｔ４下降显著（Ｐ＜０．０１）；Ｃ肽、胰岛素、睾酮升高显著（Ｐ＜０．０１）。结论：二氢埃托啡成瘾者垂体甲状腺功能受抑制，胰腺和睾酮分泌升高
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| 关 键 词： | 二氢埃托啡；海洛因瘾；促甲状腺素；三碘甲状腺原氨酸；甲状腺素；胰岛素；肽类；睾酮；物质依赖性 |
Thyroid gland function,pancreas secretion,and testosterone concentrations in dihydroetorphine addicts |
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| WANG zhi-Gang, ZHAO Jin-Shuan, ZHAO Zhu-Lin,HAN Yan-Qiu,YANG Yu-Zhan, FU Jin-Chun,LI Xiu-Lian, ZHANG Xian-Wu. Thyroid gland function,pancreas secretion,and testosterone concentrations in dihydroetorphine addicts[J]. Chinese Journal of New Drugs and Clinical Remedies, 1996, 0(6) |
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| Authors: | WANG zhi-Gang ZHAO Jin-Shuan ZHAO Zhu-Lin HAN Yan-Qiu YANG Yu-Zhan FU Jin-Chun LI Xiu-Lian ZHANG Xian-Wu |
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| Abstract: | AIM:To study pituitary-thyroid,pancreas,and testis functions in dihydroetorphine addicts. METHODS:Radioimmunoassay was used to determine the blood constituents in 11 male dihydroetorphine addicts,29 male heroin addicts,and 26 healthy men. RESULTS:In dihydmetorphine addicts,the blood concentrations of TSH,T3,and T4 were lower while C-peptide,insulin,and testosterone levels in blood were higher than those in healthy men and heroin addicts. CONCLUSION:The male dihydroetorphine addicts showed inhibited pituitary-thyroid functions and raised pancreatic and testicular functions. |
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| Keywords: | dihydroetorphine heroin dependence thyrotropin triiodothyronine thyroxine insulin peptides testosterone substance dependence |
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