A review of the solitary cutaneous T‐cell lymphomas |
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Authors: | Mina S Ally Alistair Robson |
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Institution: | 1. Department of Dermatology, Stanford University School of Medicine, , Redwood City, CA, USA;2. St. John's Institute of Dermatology, St. Thomas' Hospital, , London, UK |
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Abstract: | Cutaneous T‐cell lymphomas (CTCL) account for almost 65‐92% of all cutaneous lymphomas, many of which usually present with multiple lesions. However, a number of well‐recognized and rare types of CTCL, including mycosis fungoides, can present in isolated fashion. These solitary lesions often run a relatively indolent clinical course but often pose diagnostic difficulties. We review histopathologically challenging solitary cutaneous T‐cell lymphomas, including criteria for diagnosis, clinical course and prognosis, particularly for primary cutaneous CD4+ small/medium pleomorphic lymphoma and indolent CD8+ lymphoid proliferation of acral sites. In addition, we suggest an algorithm and nomenclature to aid in the diagnosis of such problematic lesions. |
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Keywords: | solitary mycosis fungoides pagetoid reticulosis indolent CD8+ lymphoid proliferation of acral sites primary cutaneous CD4+ small/medium pleomorphic lymphoma |
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