多囊性肾透明细胞癌临床病理分析

目的:探讨多囊性肾透明细胞癌的临床病理特点,以加深对本瘤的认识。方法:对2例多囊性肾透明细胞癌的临床及病理特点进行分析,并结合文献复习。结果:本瘤生长缓慢,临床上患者多无自觉症状;病理检查大体见肿物由大小不等的囊腔构成。镜下囊内壁主要由单层立方或柱状上皮被覆,部分为多层上皮并有乳头形成,瘤细胞胞质空亮,无明显异型性。癌细胞免疫组化示:cytokeratin、CEA和vimentin阳性表达。结论:多囊性肾透明细胞癌是一种罕见的肾癌的病理类型,临床极易误诊,分化程度高,属低度恶性的肿瘤,预后较好。

A Clinicopathological Study on Two Cases with Multilocular Cystic Renal Clear Cell Carcinoma

Purpose To study the clinical and pathological features of multilocular cystic renal clear cell carcinoma.(MLCRCCC).Methods Two cases of multilocular cystic renal clear cell carcinoma were stained with immunohistochemistry and the literature was reviewed.Results The tumor grow slowly, It was made up of multi-morphological cysts and The majority of carcinoma cells was clear cells and showed cytokeratin,CEA and vimentin positivitise by immunohistochemical staining.Conclusion MLCRCCC is a rare histologic subtype of renal cell carcinoma.It originates from tubular epithelial cells of the kidney and appears to be a low-grade malignant neoplasm and has a good prognosis.