| 脂联素血管保护机制研究进展 |
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| 引用本文： | 张凌娟. 脂联素血管保护机制研究进展[J]. 上海交通大学学报(医学版), 2010, 30(9): 1164-1167. DOI: 10.3969/j.issn.1674-8115.2010.09.035 |
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| 作者姓名： | 张凌娟 |
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| 作者单位： | 上海交通大学,医学院附属新华医院内分泌科,上海200092 |
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| 摘 要： | 脂联素是一种由脂肪细胞分泌的血浆蛋白,具有心血管保护作用。脂联素通过多种信号通路,发挥抗炎、抗氧化、抗动脉粥样硬化、改善微循环及双向调节血管新生的作用。文章就脂联素血管保护机制的研究进展作一综述。
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| 关 键 词： | 脂联素 动脉粥样硬化 信号通路 |
Research progress of vascular protection mechanism of adiponectin |
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| ZHANG Ling-juan. Research progress of vascular protection mechanism of adiponectin[J]. Journal of Shanghai Jiaotong University:Medical Science, 2010, 30(9): 1164-1167. DOI: 10.3969/j.issn.1674-8115.2010.09.035 |
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| Authors: | ZHANG Ling-juan |
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| Affiliation: | Department of Endocrinology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China |
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| Abstract: | Adiponectin is an abundant plasma protein secreted from adipocytes that elicits protective effects in the vasculature and myocardium. Adiponectin suppresses oxidative stress, inhibits inflammatory signaling cascades, ameliorates microvascular circulation and regulates angiogenesis via multiple signal pathways. The research progress of vascular protection mechanism of adiponectin is reviewed in this paper. |
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| Keywords: | adiponectin atherosclerosis signal pathway |
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