18F-FDG PET/CT寻找多发性骨转移瘤原发灶的临床应用价值

目的探讨18F-FDGPET/CT寻找多发性骨转移瘤原发灶的临床应用价值。方法回顾性分析77例多发性骨转移瘤患者行18F-FDGPET/CT寻找原发病灶的情况,并与病理结果进行对照。结果在77例患者中,18F-FDGPET/CT发现原发灶的共有44例,其中40例（51.9%）经手术或活检病理证实为原发灶,另有4例为假阳性。未找到原发灶的37例多发性骨转移瘤中,1例术后经病理证实为胃印戒细胞癌,其余36例随访时仍未找到原发灶。18F-FDGPET/CT寻找多发性骨转移瘤原发灶的灵敏度为97.6%,特异度为88.9%,符合率为93.5%。结论 18F-FDGPET/CT寻找多发性骨转移瘤原发灶有一定的临床应用价值,对制定合适的治疗方案有积极作用。

Clinical application of 18F-FDG PET/CT in detection of primary tumors of multiple bone metastatic tumors

Objective To explore the clinical application of 18F-FDG PET/CT in detection of primary tumors of multiple bone metastatic tumors. Methods The results of detection of primary tumors by 18F-FDG PET/CT in 77 patients with multiple bone metastatic tumors were retrospectively analysed, and comparisons were conducted with pathological findings. Results In all the 77 patients, 18F-FDG PET/CT revealed 44 suspected primary tumors, among whom 40 were confirmed by surgical or pathological examinations, and the other 4 were false positive cases. In the 37 patients without primary tumors detected by 18F-FDG PET/CT, one was diagnosed as gastric Signet ring cell carcinoma by pathological examination after operation, and primary tumors were not found in the other 36 patients during the follow up. The sensitivity, specificity and accuracy of 18F-FDG PET/CT in detection of primary tumors were 97.6%, 88.9% and 93.5%, respectively. Conclusion 18F-FDG PET/CT has definite value in detection of primary tumors of multiple bone metastatic tumors.