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Prospective Evaluation of the Rate and Impact of Hemolysis on Intraoperative Parathyroid Hormone (IOPTH) Assay Results |
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| Authors: | Jacob Moalem Daniel T Ruan Rachel L Farkas Wen T Shen Steve Miller Quan-Yang Duh Orlo H Clark and Electron Kebebew |
| Institution: | (1) Department of Surgery, University of Rochester Medical Center, Rochester, NY, USA;(2) Department of Surgery, Brigham and Women’s Hospital, Boston, MA, USA;(3) Department of Surgery, Mount Zion Medical Center, University of California, San Francisco, San Francisco, CA, USA;(4) Surgical Service, Veterans’ Affairs Medical Center, San Francisco, CA, USA;(5) Department of Laboratory Medicine, Mount Zion Medical Center, University of California, San Francisco, San Francisco, CA, USA |
| Abstract: | BackgroundIntraoperative parathyroid hormone (IOPTH) is commonly used during minimally invasive parathyroidectomy. Retrospective evidence suggested that hemolysis may artificially lower IOPTH results. Falsely decreased IOPTH measurements could result in either failed parathyroidectomy or unnecessary bilateral neck exploration. |
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