维奥欣对高原性心脏病患者血液流变学及血脂的影响

目的　观察维奥欣对高原性心脏病患者血液流变学指标及血脂水平的影响。　方法　 5 7例高原性心脏病患者随机分为治疗组 30例 (维奥欣组 )和对照组 2 7例 (复方丹参片组 ) ,在常规治疗基础上治疗组给予维奥欣片 16 0mg ,每日 3次 ;对照组给予复方丹参片 3片 ,每日 3次 ,疗程均为 8周。两组患者在治疗前后测定全血低切粘度 (LSR)、全血高切粘度 (HSR)、血浆粘度 (ηP)、红细胞压积 (HCT)和血清胆固醇 (TC)、甘油三酯 (TG)、低密度脂蛋白 (LDL)、高密度脂蛋白 (HDL)水平。　结果　治疗组TC、TG、LDL水平显著下降 ,HDL水平升高 ;LSR、HSR、ηP、HCT显著降低 (P <0 0 5 ) ,而对照组差别不显著。 　结论　维奥欣能显著改善高原性心脏病患者血液流变学指标和降低血脂水平 ,治疗高原性心脏病安全、有效。

EFFECT OF WEI-AO-XIN TABLET ON HEMORRHEOLOGY AND LEVEL OF LIPOID IN PATIENTS WITH HIGH ALTITUDE HEART DISEAS

Objective To observe the effect of Wei-Ao-Xin tablet on hemorrheology and level of lipoid in patients with high altitude heart disease. Methods 57 cases with high altitude heart disease were randomly divided into two groups.The patients received treatment for 8 weeks.30 cases in Wei-Ao-Xin group treated with Wei-Ao-Xin tablet 160mg,tid;27 cases in Dan-Shen group treated with Dan-Shen tablet 3#,tid.Before and after treatment,the parameters of hemorrheology and the level of lipoid were measurde in venous blood.Results The levels of lipoid and hemorrhelogy parameters were decreased remarkably (P<0.05) in Wei-Ao-Xin group comparde with Dan-Shen group.Conclusion It is safe and effective to treat high altitude heart disease by Wei-Ao-Xin tablet.