前列腺癌近距离治疗后勃起功能障碍相关的研究进展

前列腺癌近距离治疗与前列腺癌根治行切除术都能对早期前列腺癌患者起到根治的疗效,但前者发生勃起功能障碍的发生率较低。勃起功能障碍(ED)的定义为持续或反复不能达到并维持阴茎勃起状态而影响性生活,常使用国际勃起功能评分。其发生的原因可分为血管源性及非血管源性。前列腺癌近距离治疗后勃起功能障碍的治疗,是药物治疗、物理治疗及心理咨询相结合的综合性治疗。5型磷酸二酯酶抑制剂(PDE5)抑制剂和前列地尔是目前治疗前列腺近距离治疗后ED的一线用药。

Research progress on erectile dysfunction following brachytherapy for prostate cancer

Brachytherapy for prostate cancer,together with radical prostatectomy are both well-accepted treatment modalities for localized prostate cance.However,the incidence of erectile dysfunction following brachytherapy is lower as compared to that of prostatectomy.Erectile dysfunction(ED) may be defined as the consistent inability to achieve or maintain an erection sufficient to permit satisfactory sexual intercourse,and can be evaluated by International Index of Erectile Function.Studies identifying the etiology of post radiation ED as vasculogenic and nonvasculogenic.The treatment of ED after brachytherapy should be a combination of medication,physiotherapy and sexual counseling.Phosphodiesterase-5 inhibitors and alprostadil are the first line medication of ED following brachytherapy.