Synthesis of some quinoxaline derivatives containing indoline-2,3-dione or thiazolidinone residue as potential antimicrobial agents |
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| Authors: | Adel A El-Gendy Salwa El-Meligie Afaf K El-Ansary Aly M Ahmedy |
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| Institution: | 1. Organic Chemistry Department, Cairo University, 11562, Cairo, Egypt
2. Microbiology Department, Faculty of Pharmacy, Cairo University, 11562, Cairo, Egypt
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| Abstract: | The synthesis of some quinoxaline derivatives containing indoline-2,3-dione or thiazolidinone residue is described. The synthesized
derivatives were screenedin vitro for their growth inhibitory activity against six species of bacteria, viz.Staphylococcus aureus, Streptococcus faecalis, Escherichia coli, Pseudomonas aeruginosa, Serratia marcescens andMycobacterium semegmatis. Most of the compounds exhibited antimicrobial activity especially those having indoline-2,3-dione moiety. |
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| Keywords: | Quinoxalines Indoline-2 3-diones Thiazolidinones Antimicrobial activity |
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