| Abstract: | Inhibition of leukocyte migration under the influence of protein extract from a chorionepithelioma was investigated in 40 patients with trophoblastic tumors. Marked inhibition of leukocyte migration was found in patients with evidence of active tumor growth before and in the course of treatment. The exception was four patients in whom no inhibition was found either before or during treatment. The inhibition effect was absent in mos patients when the clinical course was favorable as a result of surgery and chemotherapy or of chemotherapy alone. Leukocytes of healthy donors did not react to the tumor extract in any of 24 cases.Group for Combined Methods of Treatment, Department of Gynecology, Oncologic Scientific Center, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR L. M. Shabad.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 85, No. 5, pp. 580–582, May, 1978. |
