江门市新会区华支睾吸虫病流行现状调查与分析

目的了解江门市新会区华支睾吸虫病的流行现状,确定华支睾吸虫病的高危人群,提供当地华支睾吸虫病感染因素的线索。方法采用免疫酶联吸附法检测血清中华支睾吸虫特异性抗体;采用改良加藤氏法检测粪便虫卵;采用消化法检测淡水鱼中华支睾吸虫囊蚴;进行问卷调查华支睾吸虫感染相关的生活和行为方式;同时采用病例对照方法分析影响华支睾吸虫感染的相关流行因素。结果共调查1720人,华支睾吸虫平均感染率为18.14%,男性感染率高于女性（P〈0.001）。各年龄组均有感染,感染率差异有统计学意义（P〈0.001）。共调查常见淡水鱼6种共273尾,6种淡水鱼体内均查到华支睾吸虫囊蚴。病例对照研究显示,吃半熟鱼习惯及外出饮食等行为是最重要的危险因子。结论新会区华支睾吸虫病流行范围广,感染率高,已经成为一个严重的公共卫生问题,应积极开展综合性防控工作。

Investigation on Clonorchis sinensis Infection in Jiangmen, Xinhui City

Objective To investigate the current status of Clonorchis sinensis infection in Jiangmen, Xinhui City. Methods The specific antibody of Clonorchis sinensis in serum was tested by enzyme-linked immunosorbent assay （ELISA）, and Clonorchis sinensis eggs in feces were detected by modified Kato-Katz method when the serum test was positive. The metaeercaria of Clonorchis sinensis in fresh water fish were detected by digestion assay. Questionnaire was designed to collect the life style information about eating habits, etc. By using a case-control method, the risk factors of Clonorchis sinensis infection were also analyzed. Results 1 720 subjects were studied, and 18.14% of them were infected. The infection rate was significantly higher in male than in female. The metacercaria of Clonorchis sinensis was found in all 6 species of fresh water fish. Finally, eating behaviors, such as eating out and predilection for eating not-fully boiled fish, were the most significant risk factors. Conclusion The infection rate of Clonorchis sinensis in Xinhui was relatively higher,and it has been a severe public health problem. The comprehensive control measures should be actively conducted.