首页 | 本学科首页   官方微博 | 高级检索  
     

IL-17与甲状腺功能亢进症患者血清中FT3、FT4的关系研究
引用本文:蔡安季,郝建华,张建华,张庆侠,苏卓娃,谢忠奎,李江,胡峰兰. IL-17与甲状腺功能亢进症患者血清中FT3、FT4的关系研究[J]. 广东寄生虫学会年报, 2009, 0(12): 1411-1412
作者姓名:蔡安季  郝建华  张建华  张庆侠  苏卓娃  谢忠奎  李江  胡峰兰
作者单位:广东医学院附属深圳南山人民医院检验科,深圳518052
基金项目:深圳南山科技局项目(No.2008011).
摘    要:目的探讨甲状腺功能亢进症患者血清IL-17的水平及其FT3、FT4的相关性。方法采用酶联免疫吸附试验测定30例健康对照者和30例甲亢患者血清中IL-17的水平,化学发光法检测FF3、FT4,并分析IL-17与FT3、FT4的相关性。结果甲亢组血清中的IL-17(1089.5±101.9)pg/L与正常对照gg(725.4±94.6)pg/L比较明显升高(P〈0.05);同时相关性分析表明甲亢患者血清中IL-17的表达水平与FIB、FT4的浓度呈明显的正相关[r(FT3)=0.68,r(FT4)=0.56,P〈0.05]。结论甲亢患者血清中IL—17的高表达可能与FT3、FT4激素分泌有关。

关 键 词:IL-17  甲状腺功能亢进症  FT3  FT4

Analysis of Serum IL-17, FT3 and FT4 in Hyperthyroidism Patients
CAI An-ji,HAO Jian-hua,ZHANG Jian-hua,ZHANG Qing-xia,SU Zhuo-wa,XIE Zhong-kui,LI Jiang,HU Feng-lan. Analysis of Serum IL-17, FT3 and FT4 in Hyperthyroidism Patients[J]. Journal of Tropical Medicine, 2009, 0(12): 1411-1412
Authors:CAI An-ji  HAO Jian-hua  ZHANG Jian-hua  ZHANG Qing-xia  SU Zhuo-wa  XIE Zhong-kui  LI Jiang  HU Feng-lan
Affiliation:(Department of Clinical Laboratory, the Affiliated Shenzhen Nanshan Hospital of Guangdong Medical College, Shenzhen 518052, China)
Abstract:Objective To investigate the relationship between the levels of serum IL-17 and FT3/FT4 in hyperthyroidism patients. Methods Sera from 30 normal subjects and 30 hyperthyroidism patients were analyzed. Levels of serum IL-17 were determined by enzyme-linked immunosorbent assays. FT3 and FT4 were determined by chemolumineseence. Results The level of serum IL-17 in hyperthyroidism patients (1089.5±101.9)pg/L was higher than the control subjects (725.4±94.6)pg/L. There was a positive correlation between the expression level of IL-17 and NF3,FT4 (FT3,r=0.68;FT4,r=0.56,P〈0.05). Conclusion The level of serum IL-17 in hyperthyroidism patients is correlated with the increasing level of thyroid homones.
Keywords:IL-17  hyperthyroidism  FT3  FT4
本文献已被 维普 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号