肿瘤患者感染病原菌的临床分布及耐药性分析

目的研究住院肿瘤患者感染的细菌分布及耐药情况。方法对198例住院肿瘤患者感染的病原菌进行分析．并统计其检测结果和药敏结果。结果病原菌总检出率为75．4％，革兰阴性菌占60．8％，革兰阳性菌占28．9％．真菌占10．3％，主要致病菌依次为大肠埃希菌、肺炎克雷伯菌、金黄色葡萄球菌和铜绿假单胞菌等，对大多数抗菌药物耐药。结论肿瘤患者院内感染的致病菌以阴性杆菌为主，细菌耐药性明显增强；临床应严格控制抗生素的应用以降低细菌耐药性，合理、适当选用抗菌药物对降低肿瘤患者感染非常重要。

Characterization of Antibiotic Resistance of Nosocomial Bacilli Infection in Cancer Patients

Objective To investigate the antibiotic resistance of bacilli isolated from cancer patients. Method 198 cases nosocomial infection of tumor patients were analyzed. The isolated bacilli and their antibiotic resistance were analyzed. Result The total pathogen positive rate was 75.4%, in which 60.8% were Gram-negative bacilli, 28.9% were Gram-positive bacilli and 10.3% were fungus. The most common antibiotic resistant pathogens were Escherichia coli, Klebsiella pneumoniae , Staphylococcus aureus and Pseudomonas aeurginosa. Conclusion Gram-negative bacilli were the major pathogens causing nosocomial infection in tumor patients. The antibiotic resistance was increasing obviously. Antibiotics should be used properly to decrease the drug resistance and to prevent the infection in tumor patients.