| 皮肤脱色剂研究方法 |
| |
| 引用本文： | 薛东章,张汝芝.皮肤脱色剂研究方法[J].实用全科医学,2010,8(3):381-382. |
| |
| 作者姓名： | 薛东章 张汝芝 |
| |
| 作者单位： | 薛东章,XUE Dong-zhang(安徽省蚌埠医学院第一附属医院皮肤性病科蚌埠医学院药理系,233004);张汝芝,ZHANG Ru-zhi(安徽省蚌埠医学院第一附属医院皮肤性病科,233004) |
| |
| 摘 要： | 目的总结研究皮肤脱色剂的方法。方法简述色素沉着过程，回顾性分析皮肤脱色剂的研究。结果皮肤颜色主要取决于黑素的量和位置，黑素在黑素细胞特有的细胞器即黑素体内生成。成熟的黑素体从黑素细胞的树突转移到邻近的角质形成细胞进行有序降解，含有黑素颗粒的角质形成细胞随着表皮的更替而脱离皮肤，任一环节的障碍都可影响皮肤颜色。用于评估皮肤美白制剂有效性的方法包括生物化学分析、黑素细胞培养、表皮重建、动物模型、临床评估以及无创伤性仪器检测。结论评估皮肤脱色剂的效果，在不同层面需采用不同方法。
|
| 关 键 词： | 黑素细胞 脱色剂 肤色 |
The Methods to Study Depigmenting Agents |
| |
| XUE Dong-zhang,ZHANG Ru-zhi.The Methods to Study Depigmenting Agents[J].Applied Journal Of General Practice,2010,8(3):381-382. |
| |
| Authors: | XUE Dong-zhang ZHANG Ru-zhi |
| |
| Institution: | XUE Dong-zhang,ZHANG Ru-zhi.Department of Dermatology,the First Affiliated Hospital of Bengbu Medical College,Bengbu 233004,Anhui,China |
| |
| Abstract: | Objective To summarize the methods for screening depigmenting agents.Methods The process of hyperpigmentation was briefly described,the investigative methods concerning skin depigmenting agents was retrospectively analyzed.Results The skin color mainly resulted from the amount and location of melanin.Melanin was generated in the melanocyte-specific organelles that melanosomes.Mature melanosomes transfered from the dendrites of melanocytes into neighboring keratinocytes,and then degraded orderly.Keratinocyte... |
| |
| Keywords: | Melanocyte Skin colour Depigmenting agent |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
