| 雷米芬太尼和芬太尼用于脊柱侧弯后路矫形手术的麻醉效果比较 |
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| 引用本文： | 靳艳卿,马正良,顾小萍,钟妤.雷米芬太尼和芬太尼用于脊柱侧弯后路矫形手术的麻醉效果比较[J].中国临床药理学与治疗学,2008,13(12). |
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| 作者姓名： | 靳艳卿 马正良 顾小萍 钟妤 |
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| 作者单位： | 南京大学医学院附属鼓楼医院麻醉科,南京,210008,江苏 |
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| 摘 要： | 目的:比较雷米芬太尼和芬太尼用于脊柱侧弯后路矫形手术的麻醉效果及其对术后疼痛的影响。方法:择期行脊柱侧弯后路矫形手术的患者40例,ASAⅠ～Ⅱ级,年龄11～18岁。随机分为两组:雷米芬太尼组(R组)和芬太尼组(F组)。以丙泊酚、维库溴铵和七氟醚维持麻醉。以R组(0.2μg·kg-1.min-1)和F组(1μg·kg-1.h-1)持续静脉输注维持术中镇痛。唤醒前半小时左右停用维库溴铵和镇痛药。唤醒时间为停用丙泊酚和七氟醚到患者双侧脚趾能动的时间。手术结束前R组停用雷米芬太尼后给予芬太尼2μg/kg,术后两组以芬太尼10μg·kg-1.min-1持续静脉镇痛,随访患者术后24h内的疼痛情况。结果:R组术中唤醒时间(12.3±5.7)min明显短于F组(21.6±6.5)min(P<0.01)。两组患者术后镇痛满意,术后疼痛评分(VAS评分)两组间比较差异无统计学意义。结论:在脊柱侧弯后路矫形手术中,R组患者术中唤醒明显快于F组。术中停用雷米芬太尼(0.2μg·kg-1.min-1)后及时追加芬太尼,术后未诱发明显的痛觉过敏。
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| 关 键 词： | 唤醒试验 七氟醚 雷米芬太尼 脊柱手术 |
Comparison on anesthetic effects of remifentanil and fentanyl for posterior scoliosis correction |
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| JIN Yan-qing,MA Zheng-liang,GU Xiao-ping,ZHONG Yu.Comparison on anesthetic effects of remifentanil and fentanyl for posterior scoliosis correction[J].Chinese Journal of Clinical Pharmacology and Therapeutics,2008,13(12). |
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| Authors: | JIN Yan-qing MA Zheng-liang GU Xiao-ping ZHONG Yu |
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| Institution: | JIN Yan-qing; MA Zheng-liang; GU Xiao-ping; ZHONG Yu Department of Anesthesiology; Drum Tower Hospital; Medical School of Nanjing University; Nanjing 210008; Jiangsu; China; |
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| Abstract: | AIM:To compare the effects of remifentanil and fentanyl for posterior scoliosis correction and the influences on postoperative pain.METHODS:Forty patients scheduled for posterior scoliosis correction(ASAⅠ-Ⅱ,aged 11-18 years)were randomly divided into group remifentanil(group R)and group fentanyl(group F).Anesthesia was maintained with propofol,vecuronium bromide and sevoflurane.Intravenous remifentanil(0.2 μg·kg-1·min-1)and fentanyl(1 μg·kg-1·h-1)were continuously administered for analgesia.Vecuronium bromi... |
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| Keywords: | wake-up test sevoflurane remifentanil spinal surgery |
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