| 老年患者颅内外动脉硬化与炎性因子关系的临床研究 |
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| 引用本文： | 符晓艳,贾晓军,陈阳,许志强,周华东. 老年患者颅内外动脉硬化与炎性因子关系的临床研究[J]. 重庆医学, 2009, 38(11) |
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| 作者姓名： | 符晓艳 贾晓军 陈阳 许志强 周华东 |
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| 作者单位： | 第三军医大学第三附属医院野战外科研究所神经内科,重庆,400042 |
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| 摘 要： | 目的 观察老年患者颅内外动脉硬化发生特点及其与炎性因子的关系.方法 随机选择老年患者2 115例,经螺旋CT脑血管成像、数字减影CT全脑血管造影检查有无颅内外动脉硬化,进行临床资料收集和血清炎性因子测定.结果 2 115例老年患者中颅内外动脉硬化311例(14.70%),无颅内外动脉硬化1 804例(85.30%).无颅内外动脉硬化者与颅内外动脉硬化者比较血清白介素-6[(92.70±46.80)与(72.88±25.12)pg/mL]、肿瘤坏死因子[(36.27±24.11)与(33.96±14.78)g/L]及超敏C反应蛋白[(1.73±1.43)与(1.06±0.65)mg/L]检测均升高,差异有统计学意义(P<0.05).结论 颅内外动脉硬化的发生与炎性因子变化密切相关,通过炎性因子变化可以监测动脉硬化发生和转归过程.
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| 关 键 词： | 老年患者 动脉硬化 炎性因子 |
A clinical study of extracranial-intracranial rterial sclerosis and inflammation factor |
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| FU Xiao-yan,JIA Xiao-jun,CHEN Yan,et al.. A clinical study of extracranial-intracranial rterial sclerosis and inflammation factor[J]. Chongqing Medical Journal, 2009, 38(11) |
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| Authors: | FU Xiao-yan JIA Xiao-jun CHEN Yan et al. |
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| Affiliation: | FU Xiao-yan,JIA Xiao-jun,CHEN Yan,et al.(Department of Neurology,the Third Affiliated Hospital,Third Military Medical University,Chongqing 400042,China) |
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| Abstract: | Objectives To investigate the characteristic of extracranial-intracranial arterial sclerosis and the relationship with inflammation factor.Methods From 2 115 participants,aged 65 years old and over,were randomly selected.All participants were screened with digital subtraction angiography(DSA),CT angiography(CTA) and a baseline screening.At baseline screening,the following data were collected:demographic data and neuropsychological test.Results Extracranial-intracranial arterial sclerosis were more frequentl... |
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| Keywords: | arterial sclerosis inflammation factor |
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