| 卵巢癌TIL细胞杀伤活力的研究 |
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| 引用本文： | 李慧芳 李彪如. 卵巢癌TIL细胞杀伤活力的研究[J]. 上海医学, 1995, 18(5): 268-270 |
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| 作者姓名： | 李慧芳 李彪如 |
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| 作者单位： | 上海第二医科大学附属瑞金医院妇产科，上海第二医科大学微生物教研室 |
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| 摘 要： | 本实验以卵巢浆液性囊腺癌及粘液性囊腺癌ＴＩＬ细胞作为效应细胞，卵巢浆液性细胞及Ｋ５６２细胞作为靶细胞，采用单个细胞毒实验法，连续观察了效应细胞和靶细胞的结合及杀伤过程，发现ＴＩＬ杀伤Ｋ５６２细胞及新鲜分离的肿瘤细胞具有相信心的形态变化过程，但是变化速存在着差异，其中浆液性囊腺癌ＴＩＬ细胞杀伤自体肿瘤细胞形态变化最快，其次是杀伤本同一组织类型细胞，最差的粘液性囊腺癌的ＴＩＬ细胞杀伤异体浆液性囊腺癌细
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| 关 键 词： | 淋巴细胞 卵巢肿瘤 杀伤活力 肿瘤细胞 |
THE STUDY ON CYTOTOXIC ACTIVITY OF TUMOR-INFILTRATING LYMPHOCYTES (TIL)FROM OVARIAN CANCER |
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| Li Hui- fang,et al.. THE STUDY ON CYTOTOXIC ACTIVITY OF TUMOR-INFILTRATING LYMPHOCYTES (TIL)FROM OVARIAN CANCER[J]. Shanghai Medical Journal, 1995, 18(5): 268-270 |
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| Authors: | Li Hui- fang et al. |
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| Abstract: | serial observation was made by means of inverted microscopy on the mixtureof cultured TIL, K562 and tumor cells from patients with ovarian cancer. The authorshad observed the whole interaction between the effect cells and the target cells, andfound out same killing process of TIL on K562 and tumor cells from cancer patients,but the killing speed was different. The killing speed of TILs from serous cystadeno- carcinoma against autologous tumor cells was fast, that of TILs against all ogeneicovarian tumor cells was less fast, and that of TILs from mucinous adenocarcinomaagainst tumor cells from adenocarcimona was slow. this observation will be helpfulto clinical treatment |
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| Keywords: | Tumor- infiltrating lymphocyte Ovarian cancer |
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