Complementation between mutants of CHO cells resistant to a variety of plant lectins期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Complementation between mutants of CHO cells resistant to a variety of plant lectins

Authors:	Dr. Pamela Stanley Louis Siminovitch

Affiliation:	(1) Department of Medical Genetics, University of Toronto, Medical Sciences Building, M5S 1A8 Toronto, Ontario, Canada;(2) Department of Cell Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, 10461 Bronx, New York

Abstract:	Chinese hamster cell mutants resistant to the lectins PHA, WGA, RIC, LCA, and CON A were previously grouped into 8–10 distinct phenotypes on the basis of their unique patterns of lectin resistance and lectin-binding properties. All but one of these classes of lectin-resistant (Lec^R) mutants behave recessively in somatic cell hybrids. One ricin-resistant class ( $left( {Ric^{R_{II} } } right)$ behaves dominantly. Test for complementation, by measuring the lectin-resistant properties of appropriate hybrids, show that seven distinct complementation groups can be delineated among the phenotypically recessive mutants.

Keywords:
本文献已被 SpringerLink 等数据库收录！