| HPLC测定石榴健胃丸中桂皮醛和胡椒碱的含量 |
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| 引用本文： | 倪琳, 杨锡. HPLC测定石榴健胃丸中桂皮醛和胡椒碱的含量[J]. 中国现代应用药学, 2012, 29(1): 67-69. |
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| 作者姓名： | 倪琳 杨锡 |
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| 作者单位： | 1.甘肃省食品药品检验所，甘肃省中药品质与安全评价工程技术研究中心，兰州730000 |
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| 摘 要： | 目的 建立高效液相色谱法同时测定石榴健胃丸中桂皮醛、胡椒碱含量的方法。方法 色谱柱采用CAPCELL PAK C18( 4.6 mm×250 mm，5 mm)柱；流动相为乙腈-水(40∶60)；流速：1.0 mL·min-1；检测波长：290 nm；柱温：30 ℃。结果 桂皮醛在1.149 5～13.793 5 μg之间呈良好的线性关系，平均回收率为97.27%，RSD为1.39%(n=6)；胡椒碱在0.726 4～2.724 μg之间呈良好的线性关系，平均回收率为96.51%，RSD为1.39%。结论 本法简便、准确，专属性强，可作为控制石榴健胃丸质量的方法。
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| 关 键 词： | 石榴健胃丸 桂皮醛 胡椒碱 高效液相色谱法 |
| 收稿时间： | 2011-05-16 |
| 修稿时间： | 2011-08-02 |
Determination of Cinnamaldehyde and Piperine in Shiliu Jianwei Pill by HPLC |
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| NI Lin, YANG Xi. Determination of Cinnamaldehyde and Piperine in Shiliu Jianwei Pill by HPLC[J]. Chinese Journal of Modern Applied Pharmacy, 2012, 29(1): 67-69. |
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| Authors: | NI Lin YANG Xi |
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| Affiliation: | 1.Gansu Provincial Institute of Food and Drug Control, Gansu Province Traditional Chinese Medicine Quality and Safety Evaluation of Engineering Technology Research Center, Lanzhou 730000, China |
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| Abstract: | OBJECTIVE To determine the content of Cinnamaldehyde and Piperine in Shiliu jianwei Pill. METHODS The analysis was performed on a CAPCELL PAK C18 Column（4.6 mm×250 mm, 5 um）at 30℃ with acetonitrile-water （40 ： 60）as the mobile phase and the flow rate of 1.0 mL.min-1. The detection wavelength was 290nm. RESULITS Cinnamaldehyde have good linearity in the range of 1.149 5-13.793 5 ug（r=0.999 7）. The average recovery was 97.27% and RSD was 1.39% （n=6）. Piperine have good linearity in the range of 0.726 4-2.724 ug, （r=0.999 1） respectively. The average recovery was 96.51% and RSD was 1.39% （n=6）. CONCLUSION The established method is accurate, reliable and specific. The quality of the pill can be controlled by the method. |
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| Keywords: | Shiliu Jianwei Pill Cinnamaldehyde Piperine HPLC |
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