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CO_2气腹对妊娠中晚期大鼠血清胎盘泌乳素含量的影响
引用本文:蔡东红,张颖,廖靖,邹琳. CO_2气腹对妊娠中晚期大鼠血清胎盘泌乳素含量的影响[J]. 中国妇幼保健, 2011, 26(20): 3151-3152
作者姓名:蔡东红  张颖  廖靖  邹琳
作者单位:广东医学院附属医院妇产科,广东湛江,524001
基金项目:广东省科技计划项目〔No:2008B030301019〕
摘    要:目的:探讨妊娠中晚期不同CO2气腹时间对大鼠HPL含量的影响。方法:建立妊娠中期CO2气腹的大鼠模型,分实验组及对照组,采用固相夹心法酶联免疫吸附实验(ELISA)检测妊娠中晚期大鼠HPL的含量变化。结果:实验组妊娠中期大鼠HPL值与对照组相比,无统计学意义(P>0.05);妊娠晚期,常气腹压1 h组与2 h组(B、C组)HPL值与非气腹组(A组)相比,无统计学意义(P>0.05);高气腹压1 h组与2 h组(D、E组)HPL值明显低于同期非气腹组(A组),有统计学意义(P<0.01);高气腹压1 h组与2 h组HPL值低于常气腹压1 h组与2 h组,有统计学意义(P<0.05)。结论:不同孕期母鼠血液中HPL值不同,与胎盘成熟度呈正相关;不同气腹压力及时间对妊娠中期母鼠胎盘功能无明显影响,但对妊娠晚期母鼠胎盘功能有明显影响,压力越大、时间越长,影响越明显。

关 键 词:CO2气腹  胎盘功能  胎盘泌乳素

Effects of CO_2 pneumoperitoneum on serum human placental lactogen in rats with second trimester pregnancy
CAI Dong-Hong,ZHANG Ying,LIAO Jing,et al.. Effects of CO_2 pneumoperitoneum on serum human placental lactogen in rats with second trimester pregnancy[J]. Maternal and Child Health Care of China, 2011, 26(20): 3151-3152
Authors:CAI Dong-Hong  ZHANG Ying  LIAO Jing  et al.
Affiliation:CAI Dong-Hong,ZHANG Ying,LIAO Jing,et al.Department of Obstetrics and Gynecology,Affiliated Hospital of Guangdong Medical College,Zhangjiang 524001,Guangdong,China
Abstract:Objective:To investigate the concentration of serum human placental lactogen(HPL) in medium and late pregnancy rats' during different pressure and time of CO2 pneumoperitoneum.Methods:A second trimester rat models were set up for carbon dioxide pneumoperitoneum experiment.The level of chorionic gonadotropin,placental lactogen and estriol in blood plasma were examined in second and late trimester rat models with ELISA from different trestment groups under different pressure and various pneumoperitoneum durat...
Keywords:CO2 pneumoperitoneum  Placenta function  Human placental lactogen  
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