| 重组人表皮生长因子治疗儿童复发性口腔溃疡的疗效观察 |
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| 引用本文： | 胡哲勤,杨湘晖,龚博林. 重组人表皮生长因子治疗儿童复发性口腔溃疡的疗效观察[J]. 中国妇幼保健, 2011, 26(21): 3255-3257 |
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| 作者姓名： | 胡哲勤 杨湘晖 龚博林 |
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| 作者单位： | 1. 湖北省妇幼保健院口腔科,430070
2. 武汉大学口腔医学院东莞分院 |
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| 摘 要： | 目的:观察重组人表皮生长因子(金因肽,rhEGF)治疗儿童复发性口腔溃疡(RAU)的疗效。方法:109例复发性口腔溃疡患儿随机分为实验组57例,用金因肽喷于溃疡表面,3次/d;对照组52例用西瓜霜喷于溃疡表面,3次/d;比较两组溃疡愈合情况。结果:疼痛消失的时间实验组(3.92±1.53)天,对照组(5.09±2.07)天,两组比较差异有统计学意义(P<0.01);溃疡愈合时间实验组(4.97±2.21)天,对照组(6.22±2.90)天,两组比较差异有统计学意义(P<0.01)。结论:金因肽治疗儿童复发性口腔溃疡可缩短疼痛和治愈时间,值得临床推广。
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| 关 键 词： | 复发性口腔溃疡 重组人表皮生长因子 治疗 |
Observation on the clinical efficacy of recombinant human epidermal growth factor in treatment of recurrent oral ulcer in children |
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| HU Zhe-Qin,YANG Xiang-Hui,GONG Bo-Lin. Observation on the clinical efficacy of recombinant human epidermal growth factor in treatment of recurrent oral ulcer in children[J]. Maternal and Child Health Care of China, 2011, 26(21): 3255-3257 |
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| Authors: | HU Zhe-Qin YANG Xiang-Hui GONG Bo-Lin |
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| Affiliation: | HU Zhe-Qin,YANG Xiang-Hui,GONG Bo-Lin.Department of Stomatology,Hubei Maternal and Child Health Hospital,Wuhan 430070,Hubei,China |
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| Abstract: | Objective:To observe the clinical efficacy of recombinant human epidermal growth factor(rhEGF) in treatment of recurrent oral ulcer(ROU) in children. Methods:109 children with ROU were divided into two groups randomly,57 children in experimental group were treated with rhEGF,three times a day;and 52 children in control group were treated with watermelon frost,three times a day,the healing situations of ulcer in the two groups were compared. Results:The disappearance times of pain in experimental group and c... |
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| Keywords: | Recurrent oral ulcer Recombinant human epidermal growth factor Treatment |
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