透明质酸骨膜表面注射填充鼻唇沟的疗效观察

目的介绍骨膜表面注射透明质酸治疗鼻唇沟老化的注射方法。方法对146例鼻唇沟老化患者，在鼻唇沟内侧低洼处，于骨膜表面进行多点注射，使鼻唇沟内侧与鼻唇沟嵴之间的“台阶”感消失；有较明显鼻唇沟皱褶者，配合鼻唇沟皱褶处真皮下适量填充；抽取146例采用真皮或真皮与皮下组织交界处注射的病例作为对照组进行比较。结果所有患者术后效果均满意。与对照组相比，透明质酸用量差异没有统计学意义；并发症发生率明显降低，差异有统计学意义（P〈0．05）。结论骨膜表面透明质酸注射治疗鼻唇沟老化，效果理想，能降低并发症的发生率，临床效果满意。

Filling of nasolabial fold with hyaluronic acid injection in the periosteal surface

Objective To introduce the method of hyaluronic acid injection in the periosteal surface to fill the aging nasolabial fold. Methods From March 2012 to October 2013, 146 cases with nasolabial fold were filled with hyaluronic acid by multi-point injection in the periosteal surface of the lower position of medial nasolabial fold to decrease the height differences between the ridges and the groove; for the cases with o obvious fold, appropriate filling were also performed under subcutaneous. Another 146 cases which adopted dermal injection or injection at the junction between dermis and subcutaneous tissue were compared as the control group. Results All patients were satisfied with the results. Compared with the control group, there was no ob- vious statistical difference in dosage of hyaluronic acid, but the incidence rate of complications decreased signif- icantly （ P 〈 0.05 ）. Conclusion The effect of hyaluronic acid injection in the periosteal surface on nasolabial fold filling is ideal, as well as it can decrease the incidence rate of complications and get satisfactory results.