| 基于Bootstrap的中药模糊评价的多重检验 |
| |
| 引用本文： | 郭安良,陆涛,尚婧,言方荣. 基于Bootstrap的中药模糊评价的多重检验[J]. 数理医药学杂志, 2014, 0(1): 9-13 |
| |
| 作者姓名： | 郭安良 陆涛 尚婧 言方荣 |
| |
| 作者单位： | 中国药科大学生物统计与计算药学研究中心,南京210009 |
| |
| 基金项目： | 资助项目：中央高校专项业务经费JKPZ2013015;国家自然科学基金重点项目NSFC81130068 |
| |
| 摘 要： | 目的:研究Bootstrap方法结合多重检验在中药多组分鉴别中的应用。方法:运用Bootstrap方法和R软件,检验给药组与控制组、模型两两比较差异的显著性。结果:通过本方法得到了各给药组与控制组、模型组的拟合曲线,以及在组内每个分子上的检验结果。结论:在中药模糊评价中,运用Bootstrap结合多重检验方法,检验中药组分是否具有显著性差异,具有可行性。
|
| 关 键 词： | Bootstrap 多重检验 中药 模糊评价 SELDI蛋白芯片技术 |
Multiple Testing in Fuzzy Evaluation of Traditional Chinese Medicine Based on Bootstrap |
| |
| Affiliation: | Guo Anliang, et al (China Pharmaceutical University, ResearchCenter o fBiostatisticsand ComputationalPharmacy, Nanjing 210009) |
| |
| Abstract: | Objective： To investigate the application of Bootstrap combined with multiple tests in test of multiple components of traditional Chinese medicine. Methods： Bootstrap method and R software were used for testing the significance of difference among trial group, control group and model group. Results： The fit- ted curves were obtained for trial group, control group and model group first, and then we got the test re- sults on the molecule level by the proposed method. Conclusion. Bootstrap method combines with the multi- ple tests is applicable in the fuzzy evaluation of traditional Chinese medicine. |
| |
| Keywords: | Bootstrap multiple testing traditional Chinese medicine fuzzy evaluation~ SELDI proteinchip technology |
| 本文献已被 CNKI 维普 等数据库收录！ |
