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附子临床不良反应分析
引用本文:张金莲,曾昭君,张冰,余书琦. 附子临床不良反应分析[J]. 中国实验方剂学杂志, 2014, 20(18): 228-231
作者姓名:张金莲  曾昭君  张冰  余书琦
作者单位:1. 江西中医药大学药学院,南昌,330004
2. 北京中医药大学中药学院,北京,100102
基金项目:2012普通本科高校中青年教师发展计划访问学者专项资金资助项目;江西中医药大学科研基金项目(2012ZX3003,ZX1016);江西省自然科学基金项目(20114BAB205075);江西省教育厅资助项目(GJJ13617)
摘    要:通过对附子临床不良反应相关研究文献进行整理和分析,归纳总结,发现附子临床不良反应的发生与其毒性成分、超剂量使用、煎煮、药物配伍、炮制、服用方法、误诊误用、个体差异等因素有关。避免附子临床不良反应的发生应从以上因素入手,在医、药、患三方面给予重视。本文通过对附子临床应用不良反应的特点、产生原因作一探讨,为临床用药安全提供参考。

关 键 词:附子  不良反应  配伍  炮制
收稿时间:2013-09-02

Analysis Clinical Adverse Reactions of Aconiti Lateralis Radix Praeparata
ZHANG Jin-lian,ZENG Zhao-jun,ZHANG Bing and YU Shu-qi. Analysis Clinical Adverse Reactions of Aconiti Lateralis Radix Praeparata[J]. China Journal of Experimental Traditional Medical Formulae, 2014, 20(18): 228-231
Authors:ZHANG Jin-lian  ZENG Zhao-jun  ZHANG Bing  YU Shu-qi
Affiliation:College of Pharmacy, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China;College of Pharmacy, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China;School of Pharmacology, Beijing University of Traditional Chinese Medicine, Beijing 100102, China;College of Pharmacy, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China
Abstract:Through the analysis of the related research literatures on Aconiti Lateralis Radix Praeparata, we found that its clinical adverse reactions are associated with its toxic components, overdosing, decoction, drug compatibility, processing, methods of administration, misdiagnosis, misuse, individual differences and some other factors. Much attention should be paid to the factors mentioned above to avoid its clinical adverse reactions, that is to say, we should give high considerations on three aspects:clinicians, drugs and patients. This paper aims to discuss the characteristics and causes of clinical adverse reactions due to Aconiti Lateralis Radix Praeparata, so as to provide references for clinical medication safety.
Keywords:Aconiti Lateralis Radix Praeparata  adverse reactions  drug compatibility  processing
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