| 骨髓间充质干细胞在软骨组织工程中的应用 |
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| 引用本文： | 黄涛,吕刚. 骨髓间充质干细胞在软骨组织工程中的应用[J]. 中国组织工程研究与临床康复, 2008, 12(25): 4987-4990 |
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| 作者姓名： | 黄涛 吕刚 |
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| 作者单位： | 中国医科大学附属第一医院骨科,辽宁省沈阳市,110001 |
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| 摘 要： | 骨髓基质干细胞应用于软骨组织工程已近20年,这方面的研究也成为干细胞领域的研究热点.本文通过检索文献对骨髓间充质干细胞在软骨组织工程中应用的情况、取得的最新进展及面临的主要问题作一综述.随着分子生物学、生物材料学、计算机及纳米生物技术的发展,以骨髓间充质干细胞为种子细胞复合生物材料支架构建的组织工程软骨在修复关节软骨缺损中将具有广阔的应用前景.
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| 关 键 词： | 骨髓间充质干细胞 软骨组织工程 生物学特性 基质材料 骨髓间充质干细胞 软骨组织工程 应用 tissue engineering articular cartilage marrow mesenchymal stem cells bone seed combined stent widely perspective repairing defect computer biomaterial development molecular biology progress problems |
Application of bone marrow mesenchymal stem cells in cartilage tissue engineering |
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| Huang Tao,Lü Gang. Application of bone marrow mesenchymal stem cells in cartilage tissue engineering[J]. Journal of Clinical Rehabilitative Tissue Engineering Research, 2008, 12(25): 4987-4990 |
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| Authors: | Huang Tao Lü Gang |
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| Abstract: | Bone marrow stromal stem cells have been used in cartilage tissue engineering for nearly 20 years. This has been a key focus in stem cell research. This article serves to review application, progress and facing problems of bone marrow mesenchymal stem cells (BMSCs) in cartilage tissue engineering by retrieving publications. With the development of molecular biology, biomaterial, computer and nano-biotechnology, tissue-engineered cartilage constructed with BMSCs as seed cells combined with biomaterial stent has a widely application perspective in repairing articular cartilage defect. |
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