芬太尼透皮贴剂治疗肺癌癌痛疗效分析

目的：探讨芬太尼透皮贴剂在中重度肺癌癌痛治疗中的应用特点。方法：69例中重度肺癌癌痛患随机分成芬太尼透皮贴剂组和口服硫酸吗啡控释片组，评价其疗效和副反应。结果：芬太尼组36例中，未缓解3例，轻度缓解6例，部分缓解10例，明显缓解12例，完全缓解5例。口服硫酸吗啡按释片组分别为3例，5例，11例，10例及4例，两组相似。但是口服硫酸吗啡控释片组的消化道副反应明显。结论：对于慢性中重度肺癌癌痛患，芬太尼透皮贴剂是一种方便有效的镇痛药。

The clinical use of transdermal fentanyl in treatment of cancer pain of lung cancer

objective To evaluate the clinical use of transdermal fentanyl in relieve moderate to severe metastatic pain of lung cancer.Method 69 moderate or severe metastatic pain f lung cancer were randomized assigned to fentanyl treatment group and oral morphine treatment group.The response and side effect were evaluated.Results The response rate between two grpup were similar,but in oral morphine group,the side effects of digestive tract were more serious than that in fentanyl group.Conclusion Transdermal fentanyl is a effective and convenient drug to treat moderate or serious metastatic pain of lung cancer.