奥美拉唑联合法莫替丁治疗反流性食管炎的疗效分析

目的：旨在探讨奥美拉唑联合法莫替丁治疗反流性食管炎的临床疗效。方法随机将我院从2012年6月-2014年6月期间收诊的114例反流性食管炎患者分为奥美拉唑组、法莫替丁组与联合用药组，通过2个疗程的治疗，观察三组患者的临床疗效与内窥镜复查结果。结果比较三组患者的临床疗效与内窥镜复查结果显示，联合用药组中痊愈的例数与总有效率均较奥美拉唑组与法莫替丁组差异显著（P〈0.05），且奥美拉唑组与法莫替丁组相比亦有统计学差异（P〈0.05）。结论奥美拉唑联合法莫替丁治疗反流性食管炎疗效更切实，其次为奥美拉唑，最后为法莫替丁。

Analysis of the clinical curative effect on reflux esophagitis of omeprazole combined with famotidine

Objective To explore the clinical curative effect on reflux esophagitis of omeprazole combined with famotidine. Meth-ods 114 cases of reflux esophagitis patients selected from June in 2012 to June in 2014 were randomly divided into omeprazole group, famotidine group and the combination group. The clinical efficacy of three groups of patients and the endoscopic check re-sults were observed after the two courses of treatment. Results The clinical efficacy of three groups of patients and endoscopic check results were compared and showed that the cases and the total effective rate of the recovery in the combination group were significant different with the others （P〈0.05）;and compared with famotidine group, that in the omeprazole group also changed sta-tistically significantly （P〈0.05）. Conclusion The clinical curative effect on reflux esophagitis of omeprazole combined with famoti-dine was best, followed by omeprazole, and that of famotidine was the last.