脉压与冠状动脉病变严重程度关系的临床观察

目的 观察脉压与冠状动脉病变严重程度的相关性.方法 231例经冠状动脉造影确诊的冠心病患者,男165例,女66例,年龄33～ 72岁,平均(51.13±11.62)岁.行24h无创动态血压监测,按动态脉压分为三组:脉压＜40mmHg组(59例)、40～60 mmHg组(107)、＞60 mmHg组(65).冠状动脉病变严重程度用冠状动脉病变支数来评价.结果 合并高血压的患者冠状动脉双支(43.2％比9.1％)及三支(27.6％比11.2％)血管病变的患病率显著高于非高血压组；三组不同脉压的患者相比,脉压＜ 40mmHg组、40～60 mmHg组、＞60 mmHg组的患者冠状动脉三支血管病变的患病率分别为8.7％、23.5％、42.7％.结论 脉压是方便的反映大动脉弹性的参数,与冠状动脉病变严重程度密切相关,是全身心血管病的一个危险信号,可指导早期干预.

Clinical observation of the relationship between pulse pressure and coronary artery lesions

Objective To observe the correlation between pulse pressure and severity of coronary artery lesions.Methods The 24h non-invasive ambulatory blood pressure of 231 patients with coronary heart disease diagnosed by CAG,including 165 male patients and 66 female ones at the age of 33-72 years（average 51.13±11.62） were measured and divided into,based on ambulatory blood pressure,Group I,II and III with pulse pressure40mmHg（59patients）,40—60 mmHg（107patients） and 60 mmHg（65 patients）,respectively.Severity of coronary artery lesions was assessed by coronary artery disease count.Results The incidence rates of the of coronary artery lesions of two branches in patients complicated with hypertension were 43.2% and 9.1%.and the three branches of coronary artery Lesions were 27.6% and 11.2%,obviously higher than those without having hypertention,The incidence rates of patients with 3 branches of coronary artery lesions in the pulse pressure40mmHg group and 40—60 mmHg group and60 mmHg group were 8.7%、23.5%、42.7% and in the patients can be,according to different pulse pressure.Conclusion The pulse pressure reflecting？large artery elasticity is closely associated with the severity of coronary artery lLesions.It is also a risk signal indicating cardiac vascular disease for guiding early clinical intervention.