平阳霉素治疗跖疣的疗效观察

目的 评价平阳霉素治疗跖疣的临床疗效和安全性.方法 120例跖疣患者随机分为A组、B组和C组各40例,A组患者采用局部注射平阳霉素,每月1次,连续1～2次；B组患者采用CO2激光治疗,每月1次,连续1～2次；C组患者采用液氮冷冻,每月1次,连续1～2次.结果 A组患者治疗后基愈率为75.00％、显效率为17.50％、进步率为7.50％、无效率为0％,总有效率为92.50％；B组患者治疗后基愈率为52.50％、显效率为22.50％、进步率为17.50％、无效率为7.50％,总有效率为75.00％;C组患者治疗后基愈率为50.00％、显效率为22.50％、进步率为22.50％、无效率为5.00％,总有效率为72.50％.A组与B、C组疗效比较差异均有显著的统计学意义(Uc=5.3750,P=0.0204；Uc=6.4645,P=0.0110);B与C组疗效比较差异无显著的统计学意义(Uc=0.0355,P=0.8506).三组患者均无明显不良反应.结论 平阳霉素治疗跖疣是安全的、有效的.

Efficacy of pingyangmycin in treatment of patients with plantar warts

Objective To observe the efficacy safety of pingyangmycin in treatment of patients with plantar warts.Methods One hundred and twenty outpatients with plantar warts were randomly divided into group A,group B and group C,40 cases in each gorup.Patients in group A were treated with local pingyangmycin injection once a month for 1 to 2 times,those in B group were treated with carbon dioxide laser once a month for 1 to 2 times and patients in group C were treated with cryotherapy once a month for 1 to 2 times.Results The cured rate,effective rate,improved rate,invalid rate and total effective rate were 75.00%,17.50%,7.50%,0% and 92.50%,respectively.The cured rate,effective rate,improvement rate,no effect rate and total effect rates in group B were 52.50%,22.50%,17.50%,7.50% and 75.00%,respectively,and that in group C were 50.00%,22.50%,22.50%,5.00% and 72.50%,respectively.The effective rate in group A was significant higher than that of group B and C（Uc= 5.3750,P=0.0204;Uc= 6.4645,P=0.0110）.The effective rates in group B and C showed no statistically significant difference（Uc= 0.0355,P=0.8506）.Conclusion Pingyangmycin is effective and safe for treatment of patients with plantar warts.