| 前列地尔联合莫沙必利治疗2型糖尿病胃轻瘫临床观察 |
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| 引用本文： | 郑海龙,王海凤,王转锁,宋钦华.前列地尔联合莫沙必利治疗2型糖尿病胃轻瘫临床观察[J].中国热带医学,2012,12(8):974-975,986. |
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| 作者姓名： | 郑海龙 王海凤 王转锁 宋钦华 |
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| 作者单位： | 海南医学院附属医院内分泌科,海南海口,570102 |
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| 摘 要： | 目的 观察前列地尔联合莫沙必利治疗糖尿病胃轻瘫临床疗效.方法 收集我院2型糖尿病并发胃轻瘫患者60例,随机分为治疗组和对照组,每组各30例,对照组给予莫沙必利治疗,治疗组在对照组的基础上加用前列地尔,两组都给予降血糖治疗,并维持血糖相对稳定.两组均治疗4周,观察临床症状,行胃镜检查.结果 前列地尔联合莫沙必利治疗组总体有效率为93.3％(28/30)明显高于对照组的73.3％(22/30),差异有统计学意义(P＜0.05),没有明显的不良反应.结论 在糖尿病综合治疗和血糖充分控制的前提下前列地尔联合莫沙必利治疗尿病性胃轻瘫,与单用莫沙必利治疗,疗效更优,安全可行.
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| 关 键 词： | 糖尿病胃轻瘫 前列地尔 莫沙必利 |
Effect of alprostadil combined with mosapride on diabetic gastroparesis patients. |
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| Institution: | ZHENG hal-long, Wang Hai-feng, WANG Zhuan-suo, et al. (Department of Endocrinalosy of Affiliated Hospital of Hainan Medical College,Haikou 570102 ,Hainan,P. R. China) |
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| Abstract: | Objective To observe the therapeutic outcome of alprostadil combined with mosapride on diabetic gastmparesis patients. Methods A total of 60 patients with diabetic gastroparesis were randomly divided into treatment group （n=30）treated with mosapride in combination with alprostadil and control group（n=30）only treated with mosapride for a course of 4 weeks, clinical symptoms and gastroscopy were observed before treatment and 4 weeks after treatment. Results The total effeetive rate was 93.3%（28/30） higher significantly in the treatment group Compared with the control group （73.3%）（P〈0.05）. No obvious side effects were observed. Conclusion The clinical efficacy of alprostadil combined with mosapride is effective and safe for treatment of diabetic gastroparesis patients. |
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| Keywords: | Diabetic gastroparesis Alprostadil Mosapride |
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