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2017-2019年天津市某三甲医院门诊降脂药物使用情况分析
引用本文:王郁汀,赵振宇. 2017-2019年天津市某三甲医院门诊降脂药物使用情况分析[J]. 现代药物与临床, 2021, 36(3): 611-616
作者姓名:王郁汀  赵振宇
作者单位:天津医科大学朱宪彝纪念医院、天津市内分泌研究所、国家卫健委激素与发育重点实验室、天津市代谢性疾病重点实验室药剂科,天津 300134
基金项目:天津市科技计划项目(20KPHDRC00020)
摘    要:目的 汇总分析2017-2019年天津医科大学朱宪彝纪念医院门诊患者降脂药物的使用情况及发展趋势,为降脂药的临床合理应用提供科学依据.方法 选取2017-2019年天津医科大学朱宪彝纪念医院门诊降脂类药物的相关数据,采用WHO推荐的限定日剂量(DDD)、用药频度(DDDs)、日均费用(DDC)和排序比(B/A)等对选定...

关 键 词:降脂药  高脂血症  用药频度  合理用药  阿托伐他汀  国家集采政策
收稿时间:2020-12-22

Analysis on the use of hypolipidemic drugs in outpatient department of A tertiary hospital in Tianjin from 2017 to 2019
WANG Yu-ting,ZHAO Zhen-yu. Analysis on the use of hypolipidemic drugs in outpatient department of A tertiary hospital in Tianjin from 2017 to 2019[J]. Drugs & Clinic, 2021, 36(3): 611-616
Authors:WANG Yu-ting  ZHAO Zhen-yu
Affiliation:NHC Key Laboratory of Hormones and Development, Tianjin Key Laboratory of Metabolic Diseases, Chu Hsien-I Memorial Hospital & Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin 300134, China
Abstract:Objective To summarize and analyze the utilization and development trend of hypolipidemic drugs in outpatients of A tertiary hospital in Tianjin from 2017 to 2019,in order to provide references for clinical rational drug use.Methods The amount,consumption sum,frequency of drug use(DDDs),defined daily cost(DDC),and drug sequence ratio(B/A)of hypolipidemic drugs in A tertiary hospital in Tianjin from 2017 to 2019 were calculated and analyzed statistically.Results From 2017 to 2019,the sales of hypolipidemic drugs were relatively balanced,showing an upward trend year by year.Among them,the sales volume of statins-related drugs is the highest,accounting for the largest proportion,and has always occupied the first place for three consecutive years,followed by the bethe drugs.Among the specific drugs,atorvastatin(Lipitor)ranked the first for three consecutive years.Rosuvastatin calcium capsules were basically stable in 2017 and 2018,and decreased significantly in 2019.From 2017 to 2019,DDDs of atorvastatin ranked first,while fenofibrate increased steadily and ranked second.Fluvastatin was the lowest for three consecutive years.The highest DDC is probucol and the lowest was bezafibrate in 2017—2019.The B/A value of most drugs is about 1.00 and with good synchronicity in 2017—2019.Conclusion The selection and use of antihypertensive drugs for hyperlipidemia patients in A tertiary hospital in Tianjin from 2017 to 2019 are relatively,the types of drugs increased gradually,and the medication situation of patients met the requirements of the guidelines,with the implementation of the national centralized purchase policy,the drug costs of patients will drop significantly in 2019.
Keywords:hypolipidemic drugs  hyperlipidemia  rational use of drugs  atorvastatin  national centralized purchase policy
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