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基于多元统计分析的车前子药材质量等级研究
引用本文:丁若雯,魏惠珍,吕尚,宋细忠,漆俊芬,金浩鑫,曹艳霞,饶毅. 基于多元统计分析的车前子药材质量等级研究[J]. 中国现代应用药学, 2021, 38(6): 673-679
作者姓名:丁若雯  魏惠珍  吕尚  宋细忠  漆俊芬  金浩鑫  曹艳霞  饶毅
作者单位:江西中医药大学, 南昌 330000;中药固体制剂制造技术国家工程研究中心, 南昌 330006;江西省药品检查员中心, 南昌 330029;江西青春康源中药饮片有限公司, 江西 新余 338000
基金项目:国家中药标准化项目(ZYY-2017-075)
摘    要:目的 以市场收集的48批车前子药材为研究对象,构建外观性状与内在质量相关联的车前子的质量等级评价手段.方法 建立了车前子中京尼平苷酸、毛蕊花糖苷和异毛蕊花糖苷的含量测定方法并完成48批次的测定,同时对48批车前子药材进行了千粒重、长度、宽度、膨胀度、水分、总灰分、酸不溶性灰分的检测;运用主成分分析、偏最小二乘法分析、相...

关 键 词:车前子  外观性状  内在质量  质量等级
收稿时间:2020-03-05
修稿时间:2021-04-01

Study on Quality Grade of Plantaginis Semen Based on Multivariate Statistical Analysis
DING Ruowen,WEI Huizhen,LYU Shang,SONG Xizhong,QI Junfen,JIN Haoxin,CAO Yanxi,RAO Yi. Study on Quality Grade of Plantaginis Semen Based on Multivariate Statistical Analysis[J]. The Chinese Journal of Modern Applied Pharmacy, 2021, 38(6): 673-679
Authors:DING Ruowen  WEI Huizhen  LYU Shang  SONG Xizhong  QI Junfen  JIN Haoxin  CAO Yanxi  RAO Yi
Affiliation:Jiangxi University of Traditional Chinese Medicine, Nanchang 330000, China;National Pharmaceutical Engineering Center for Preparation of Chinese Herbal Medicine, Nanchang 330006, China;Jiangxi Drug Inspector Center, Nanchang 330029, China;Jiangxi Qingchun Kangyuan Herbal Sliced Medicine Co., Ltd., Xinyu 338000, China
Abstract:OBJECTIVE To construct a quality grade evaluation method of plantain seed based on 48 batches of Plantaginis Semen collected from the market. METHODS Determination method of the contents of geniposidic acid, acteoside and isoacteoside in Plantaginis Semen was established and 48 batches herbs were determined. At the same time, 1000-grain weight, length, width, swelling degree, water content, total ash content and acid insoluble ash content of 48 batches of Plantaginis Semen herbs were tested. The principal component analysis, partial least square analysis, correlation analysis, variance analysis and other mathematical statistical methods were used to select the classification index for the study of Plantaginis Semen classification. RESULTS The 1000-grain weight, swelling degree, geniposidic acid content, total contents of acteoside and isoacteoside were the key indicators of the quality evaluation of Plantaginis Semen, moreover, external index (1000-grain weight, swelling degree) and inner quality(geniposidic acid content, total contents of acteoside and isoacteoside) at the 0.01 level showed significant positive correlation, in combination with the practical situation of the market, the Plantaginis Semen quality grade standard of first class, second class and uniform goods were developed. CONCLUSION This quality grade not only evaluates Plantaginis Semen in terms of appearance characteristics, but also characterizes its internal quality difference, which satisfies the judgment rule of "plump seed is the best" and provides basis for the establishment of industry standard or national standard.
Keywords:Plantaginis Semen  appearance character  inner quality  quality grade
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