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复方雪莲胶囊联合玻璃酸钠治疗膝骨关节炎的临床研究
引用本文:李卫国,魏建新,李景龙.复方雪莲胶囊联合玻璃酸钠治疗膝骨关节炎的临床研究[J].现代药物与临床,2021,36(4):799-803.
作者姓名:李卫国  魏建新  李景龙
作者单位:安钢职工总医院 骨科,河南 安阳 455000;安阳市第七人民医院 中西医结合科,河南 安阳 455000;安阳市第一人民医院 骨科,河南 安阳 455000
基金项目:内蒙古自治区人民医院基金项目(2020YN04)
摘    要:目的 探讨复方雪莲胶囊联合玻璃酸钠治疗膝骨关节炎的临床疗效.方法 选取2016年3月—2019年5月在安钢职工总医院治疗的81例膝骨关节炎患者,随机分成对照组(40例)和治疗组(41例).对照组患者膝关节腔内注射玻璃酸钠注射液,20 mg/次,1次/周.治疗组患者在对照组的基础上口服复方雪莲胶囊,3粒/次,3次/d.两...

关 键 词:复方雪莲胶囊  玻璃酸钠注射液  膝骨关节炎  膝骨关节炎炎指数评分  软骨寡聚基质蛋白  基质金属蛋白酶13
收稿时间:2021/1/27 0:00:00

Clinical study on Compound Xuelian Capsules combined with sodium hyaluronate in treatment of knee osteoarthritis
LI Wei-guo,WEI Jian-xin,LI Jing-long.Clinical study on Compound Xuelian Capsules combined with sodium hyaluronate in treatment of knee osteoarthritis[J].Drugs & Clinic,2021,36(4):799-803.
Authors:LI Wei-guo  WEI Jian-xin  LI Jing-long
Institution:Department of Cardiovascular Medicine, Inner Mongolia People''s Hospital, Hohhot 010017, China
Abstract:Objective To observe the clinical effect of Xintong Oral Liquid in treatment of coronary heart disease angina pectoris. Methods A total of 78 patients with coronary heart disease and angina pectoris treated in the Inner Mongolia People''s Hospital from October 2019 to October 2020 were selected as the research objects. According to the treatment plan, the patients were divided into control group and observation group, with 39 cases in each group. Patients in the control group were given secondary preventive treatment of coronary heart disease and angina pectoris, and observation group was given Xintong Oral Liquid on the basis of control group, 10 mL/time, three times daily. Both groups were treated for 4 weeks. The clinical efficacy, the frequency and duration of angina pectoris attacks and the dosage of isosorbide nitrate tablets were compared between two groups. Results After treatment, the total effective rate of observation group was 89.7%, which was significantly higher than 69.2% of control group (P < 0.05). After treatment, the frequency of angina pectoris attack, the duration of each attack and the dose of isosorbide nitrate tablets were significantly decreased in two groups (P < 0.05). The frequency of angina attack, the duration of each attack and the dose of isosorbide nitrate tablets in the observation group were significantly lower than those in the control group (P < 0.05). Conclusion Xintong Oral Liquid in treatment of patients with coronary heart disease angina pectoris can improve the treatment efficiency, reduce the frequency and duration of angina pectoris attacks, and isosorbide nitrate containing dosage, the effect is better than that of western medicine alone, and is relatively safe, worthy of clinical application.
Keywords:Xintong Oral Liquid  coronary heart disease  angina  therapeutic effect  attack of angina pectoris
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