左心室无创压力-应变环评估强直性脊柱炎患者左心室收缩功能

目的 探讨无创左心室压力-应变环(LV PSL)评估强直性脊柱炎(AS)患者左心室心肌收缩功能的价值.方法 选取49例临床确诊AS患者和33名健康志愿者(对照组),根据C反应蛋白(CRP)水平将AS患者分为Ⅰ组(CRP＜10 mg/L,n=25)、Ⅱ组(CRP≥10 mg/L,n=24).比较3组常规超声心动图参数;根...

Left ventricular pressure-strain loop for evaluation on left ventricular systolic function in patients with ankylosing spondylitis

Objective To explore the value of the left ventricular pressure-strain loop(LV PSL)in evaluation on the left ventricular myocardial systolic function in patients with ankylosing spondylitis(AS).Methods Forty nine patients with AS and 33 healthy volunteers(control group)were selected.According to C reactive protein(CRP)level,AS patients were divided into groupⅠ(CRP<10 mg/L,n=25)and(CRP≥10 mg/L,n=24)groupⅡ.Conventional echocardiographic parameters were compared among 3 groups.LV PSL was constructed according to the opening and closing time of mitral valve and aortic valve,while the myocardial work parameters of left ventricle of global longitudinal strain(GLS),global work index(GWI),global effective work(GCW),global ineffective work(GWW)and global work efficiency(GWE)were obtained and compared among 3 groups.Results Among conventional echocardiographic parameters,only the E peak of mitral forward early diastole(E)/mitral annular early diastolic peak velocity(e')was significantly different among 3 groups,E/e'of groupⅠand groupⅡwere greater than that of control group(both P<0.05),and there was no significant difference of the other conventional parameters(all P>0.05).Compared with control group,GLS,GWI,GCW and GWE decreased and GWW increased in groupⅠandⅡ(all P<0.05),while GLS,GWI,GCW and GWE in groupⅡwere lower than those inⅠgroup(all P<0.05).Conclusion LV PSL could be used for early and quantitative assessment of left ventricular systolic function in patients with AS.