超声及MRI诊断妊娠期阑尾炎:Meta分析

目的 采用Meta分析方法评价超声、MRI对妊娠期阑尾炎的诊断效能.方法 检索Cochrane Library、Pubmed、Embase、中国知网、万方医学网和维普数据库中关于超声和/或MRI诊断妊娠期阑尾炎的文献,检索时间从建库至2019年9月.依据纳入及排除标准筛选文献,并进行质量评价.采用Stata15.0、M...

Ultrasound and MRI in diagnosis of appendicitis in pregnancy: Meta-analysis

Objective To observe the diagnostic value of ultrasound and MRI for appendicitis of pregnancy by meta-analysis. Methods Cochrane Library, PubMed, Embase, CNKI, Wanfang Med Online and VIP databases were searched for studies using ultrasound and/or MRI in diagnosis of appendicitis of pregnancy from published up to September 2019. Stata15.0 and Meta-Disc1.4 software were used for statistical analysis. Results Nineteen articles (2 379 patients with suspected appendicitis of pregnancy) were enrolled, including 4 articles using only ultrasound, 11 articles using only MRI and 4 articles using both ultrasound and MRI at the same time. In diagnosis of appendicitis of pregnancy, the sensitivity of ultrasound was 0.68 (95%CI[0.60, 0.75]) and specificity was 0.98 (95%CI[0.95, 0.99]), the diagnostic odds ratio was 12.53 (95%CI[5.78, 27.19]) and area under the receiver operating characteristic (ROC) curve (AUC) was 0.86; while the sensitivity of MRI was 0.95 (95%CI[0.91, 0.98]) and specificity was 0.98 (95%CI[0.97, 0.98]),the diagnostic odds ratio was 331.84[95%CI (161.42, 682.16)] and AUC was 0.99, significantly higher than AUC of ultrasound (Z=7.41, P<0.001). Conclusion The diagnostic efficacy of MRI for appendicitis in pregnancy was significantly higher than that of ultrasound.