鹅不食草正丁醇部位化学成分研究

[目的]对鹅不食草干燥全草乙醇提取物正丁醇部位的化学成分进行研究,为鹅不食草的系统研究和开发利用提供物质基础.[方法]通过大孔吸附树脂、Sephadex LH-20色谱、ODS柱色谱、薄层色谱和高效液相色谱等现代色谱分离手段对鹅不食草干燥全草的正丁醇部位化学成分进行系统分离,通过对其理化性质及谱学数据的分析,对分离所得...

Study on chemical constituents from n-BuOH extract of Centipeda minima (L.) A.Br.et Aschers

[Objective]To investigate the chemical constituents from the n-BuOH extracts of the whole plants of Centipeda minima(L.)A.Br.et Aschers.In order to lay the foundation of systematic research and exploration.[Methods]The compounds were isolated and purified systematically by means of macroporous resin,Sephadex LH-20 chromatography,ODS column chromatography,preparative-thin layer chromatography and preparative-HPLC,the structure of these compounds were identified by NMR and HR-ESI-MS.[Results]The 14 known compounds were identified as luteolin-7-O-β-D-glucopyranoside,quercetin-3-O-β-D-glucopyranoside,apigenin-7-O-β-D-glucuronide,nudicaucins A,guaiacin D,chlorogenic acid,4,5-O-dicaffeoyquinic acid methyl ester,p-hydroxy-benzoic acid,salicylic acid,sinapic acid,sinapic acid methyl ester,ferulic acid,caffeic acid methyl ester and syringic acid.[Conclusion]Compounds 1-14 were obtained from the genus of Centipeda Lour.for the first time.