In vitro susceptibilities of 11 clinical isolates of Exophiala species to six antifungal drugs |
| |
Authors: | Meletiadis J Meis J F de Hoog G S Verweij P E |
| |
Institution: | Department of Medical Microbiology, University Hospital Nijmegen, The Netherlands. j.meletiadis@mmb.azn.nl |
| |
Abstract: | The antifungal activities of miconazole, terbinafine, itraconazole, UR 9825, voriconazole and amphotericin B against 11 clinical isolates of Exophiala spp. were tested by the broth microdilution method. All drugs were very active against Exophiala spp.. The 90% minimal inhibitory concentration (MIC90) ranged from 0.125 to 1 microgram ml-1. Terbinafine was the most active drug against Exophiala spinifera, Exophiala dermatitidis and Exophiala castellanii and seems to be a promising agent in the treatment of infections caused by these fungi. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|