The effect of various incorporated doses of131I on immunological reactions of the organism

Administration of radioisotope¹³¹I at 148 kBq/g body weight results in an inhibition of the primary immune response and in a decrease of proliferating activity of mouse lymphocytes in response to alloantigen stimulation. The number of antibody-producing spleen cells for immunization of mice with sheep erythrocytes diminished after administration of¹³¹I at 74 kBq/g animal weight. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 121, No. 6, pp. 664–666, June, 1996