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199例药源性过敏性休克报告分析
引用本文:王晓瑜,杜文民,王宏敏,徐建龙. 199例药源性过敏性休克报告分析[J]. 世界临床药物, 2006, 27(6): 330-333
作者姓名:王晓瑜  杜文民  王宏敏  徐建龙
作者单位:上海市药品不良反应监测中心;上海市药品不良反应监测中心;上海市药品不良反应监测中心;上海市药品不良反应监测中心
摘    要:目的探讨各类药物导致过敏性休克的规律和特点。方法对2005年上海市药品不良反应监测中心药品不良反应数据库内199例药源性过敏性休克报告进行汇总分析。结果抗感染药物较易引起过敏性休克;药源性过敏性休克与年龄无关,未见性别差异,以静脉给药方式导致的过敏性休克发生率最高。结论应重视药品不良反应监测,合理用药,预防过敏性休克发生。

关 键 词:药源性疾病  过敏性休克  不良反应
文章编号:1672-9188(2006)06-330-04
收稿时间:2006-04-26
修稿时间:2006-04-26

Retrospect Analysis of 199 Cases of Drug-induced Anaphylactic Shock
WANG Xiao-Yu,DU Wen-Min,WANG Hong-Min,XU Jian-Long. Retrospect Analysis of 199 Cases of Drug-induced Anaphylactic Shock[J]. WORLD CLINICAL DRUGS, 2006, 27(6): 330-333
Authors:WANG Xiao-Yu  DU Wen-Min  WANG Hong-Min  XU Jian-Long
Affiliation:Shanghai Center forAdervse Drug Reaction Monitoring, Shanghai 200040
Abstract:objective To investigate the rule and characteristics of drug-induced anaphylactic shock(AIAS). Methods An analysis was conducted on 199 cases of drug-induced AIAS. Results Antibacterial may cause AIAS easily.There is no correlation between AIAS and age. Of the total drug-induced AIAS cases, 88.95% were administered by iv, which dominate the first place in the terms of the AIAS rate. Conclusion We should be emphasize ADR monitoring,rational use of drug and prevention of AIAS.
Keywords:drug-induced disease  anaphylactic shock(AIAS)  adverse drug reactions(ADR)
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