| 骨形态发生蛋白的成骨作用及其在骨组织工程中的应用 |
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| 引用本文： | 徐世旭,阳富春. 骨形态发生蛋白的成骨作用及其在骨组织工程中的应用[J]. 医学综述, 2008, 14(2): 193-195 |
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| 作者姓名： | 徐世旭 阳富春 |
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| 作者单位： | 1. 广西医科大学研究生院,南宁,530021
2. 广西医科大学第一附属医院创伤骨科中心,南宁,530021 |
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| 摘 要： | 骨形态发生蛋白成骨作用早已被证实,但是如何使其稳定高效的发挥成骨作用是研究的热点也是难点。基因重组、基因转染是分子生物学研究的新进展,为组织工程的深入发展提供理论和技术基础。基因工程化骨形态发生蛋白的应用在骨组织工程中具有广阔的前景。现就骨形态发生蛋白的成骨机制及其在骨组织工程中的应用进行综述。
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| 关 键 词： | 骨形态发生蛋白 组织工程 临床应用 |
| 文章编号： | 1006-2084（2008）02-0193-03 |
| 收稿时间： | 2007-04-14 |
| 修稿时间： | 2007-12-17 |
Osteogenesis and its Application in Bone Tissue Engineering of Bone Morphogenetic Protein |
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| XU Shi-xu,YANG Fu-chun. Osteogenesis and its Application in Bone Tissue Engineering of Bone Morphogenetic Protein[J]. Medical Recapitulate, 2008, 14(2): 193-195 |
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| Authors: | XU Shi-xu YANG Fu-chun |
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| Affiliation: | XU Shi-xu , FANG Fu-chun. ( 1. Guangxi Medical University, Nanning 530021, China ; 2. Center for trauma Orthopedics , the First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China ) |
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| Abstract: | The osteogenesis of bone morphogenetic protein had been verified.But how to make then play ossification with stability and high-performance is the hot and difficult spot.Gene recombination and gene transfection are the new progresses in molecular biology,which provides theory and technology basis for further study of tissue engineering.The application of genetic bone morphogenesis protein has the broad prospects in bone tissue engineering.This article makes a brief review on the BMPs about osteogenestic mechanism as well as the application in bone tissue engineering. |
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| Keywords: | Bone morphogenesis protein Tissue engineering Clinical application |
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