骨疏康对颈椎病合并骨质疏松症老年患者桡骨远端超声波传导速度及血清钙、磷的影响

背景颈椎病合并骨质疏松症在老年患者中的发病率较高,影响患者的生活质量.目的观察补肾中成药骨疏康治疗老年颈椎病合并骨质疏松症的疗效.设计以患者为研究对象的随机对照研究.单位一所省级中医院骨科.对象研究对象为2002-06/2003-12河南省中医院住院患者及部分门诊患者50例.方法50例老年颈椎病合并骨质疏松症患者,随机分为治疗组30例,对照组20例.治疗组用骨疏康治疗,10g/次,2次/d;对照组用颈复康治疗,6g/次,2次/d,疗程均为6个月.主要观察指标分别观测两组患者治疗前后临床症状改善情况,X射线表现、骨密度、血清钙磷变化情况.结果两组均有治疗作用,有效率治疗组为93%,优于对照组(75%)(P＜0.05),两组患者桡骨远端超声波传导速度(SOS),治疗组治疗前后分别为(3934±125),(3 990±105)m/s,对照组分别为(3 935±110),(3 940±123)m/s,两组相比较,差异有显著性意义(P＜0.05),对照组治疗前后SOS差异无显著性意义(P＞0.05),两组患者治疗前后血清钙、磷均无明显差别(P＞0.05).结论补肾中成药骨疏康对老年颈椎病合并骨质疏松症有良好疗效.

Effect of gushukang on remote ultrasonic conductive speed in radius and serum calcium and phosphorus in senile patients with cervical spondylosis complicated with osteoporosis

BACKGROUND: The morbidity of cervical spondylosis complicated with osteoporosis is rather high in senile patients, which affects the life quality.OBJECTIVE: To observe the therapeutic effects of gushukang, the Chinese herbal patent for kidney tonification on senile cervical spondylosis complicated with osteoporosis.DESIGN: Random control study based on patients.SETTING: Orthopedics department in a provincial hospital of traditional Chinese medicine.PARTICIPANTS: Fifty cases of senile cervical spondylosis complicated with osteoporosis collected from the inpatients and outpatients in Henan Hospital of Traditional Chinese Medicine from .June 2002 to December 2003.METHODS: Fifty cases of senile cervical spondylosis complicated with osteoporosis were randomized into experimental group(30 cases) and the control(20 cases) . In experimental group, gushukang was prescribed, 10 g/time and twice a day. In the control, jingfukang was prescribed, 6 g/time,twice per day. The course of treatment was 6 months.MAIN OUTCOME MEASURES: To observe the improvement of therapeutic effects, X-ray manifestation, bone density, serum calcium and phosphorus before and after treatment in two groups.RESULTS: The therapeutic effects were obtained in both groups. The effective rate was 93％ in treatment group, better than the control (75％) ( P ＜ 0.05). Concerning to remote ultrasonic conductive speed in radius(SOS), it was(3 934 ± 125) and(3 990 ± 105) m/s before and after treatment respectively in experimental group; and was(3 935 ± 110) and(3 940 ± 123) m/s in the control, indicating significant difference( P ＜ 0. 05) . The difference in SOS before and after treatment in the control was not significant ( P ＞ 0.05).There was no remarkable difference in serum calcium and phosphorus before and after treatment in two groups( P ＞ 0.05).CONCLUSION: Gushukang, Chinese herbal patent for kidney tonification,provides better therapeutic effects on senile cervical spondylosis complicated with osteoporosis.