| 猪松果体提取物抗肿瘤实验研究 |
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| 引用本文： | 丁永为 李同度. 猪松果体提取物抗肿瘤实验研究[J]. 肿瘤防治研究, 1995, 22(4): 197-198,201 |
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| 作者姓名： | 丁永为 李同度 |
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| 作者单位： | 安徽省肿瘤医院 |
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| 摘 要： | 作者应用猪松果体提取物，松乐素Ａ、Ｂ、Ｃ三种制剂在小鼠肉瘤１８０（Ｓ＿（１８０）），肉瘤３７（Ｓ＿（３７））和Ｂ＿（１６）黑色素瘤研究了其抗瘤活性。松乐素Ａ、Ｂ、Ｃ对Ｓ＿（１８０）抑制率分别为１４～２２％，１７～５２．５％和１９～２１．４％（剂量为０．０５～０．２ｍｌ／天）；对Ｓ＿（３７）抑制率分别为３１～３４．６％（Ｐ＞０．０５），４．５～２２．９％和２２～２２．９％；对黑色素瘤抑制率分别为２２．７～３４．７％，３１～４５％（Ｐ＜０．０１）；２８～３１％（Ｐ＜０．０５）。因此，本实验表明，猪松果体提取物松乐素有一定的抗肿瘤作用。
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| 关 键 词： | 松乐素 猪松果体 提取物 抗肿瘤活性 Pineal body extracts Antitumor activity Songlesu |
Antitumor activity of pig pineal body extract |
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| Ding Yong-wei,et al. Antitumor activity of pig pineal body extract[J]. Cancer Research on Prevention and Treatment, 1995, 22(4): 197-198,201 |
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| Authors: | Ding Yong-wei et al |
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| Affiliation: | Cancer Hospital Of Anhui Provice, Bengbu 233004 |
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| Abstract: | The antitumor activity of the three pig pineal body extracts, Songlesu A, B and C were tested in mice Sarcoma 180 (S180), Sarcoma 37 (S37) and Melonoma (Me). The tumor inhibition rates of Songlesu A, B and C against S180 was 14- 22%, 17- 52. 5 % and 19- 21. 4% respectively under the doses of 0.05- 0. 2 ml/day ; against S37 31 - 34. 6% (P>0. 05), 4. 5- 22. 9 % and 22- 22. 9%respectively and for the Me it was 22. 7- 34. 7 %, 31- 45 % (P<0. 01), 28- 31 % (P<0. 05) respectively.Therefore , all three preparations had some antitumor activity against S180, S37 and Me. |
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| Keywords: | Pineal body extracts Antitumor activity Songlesu |
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