糖类抗原CA50放射免疫抑制试验在肿瘤诊断中的价值

 本文报道我院用CA50IRMA测定45名正常人和201树非肿瘤患者及3.36例恶性肿瘤患者血清CA50含量。 正常值为＜20ku/L, 肝癌、肠癌、肺癌的CA50值明显升高(P＜0.01), 阳性率分别为79.1%(53/67)、36.4%(16/44、34.9%(29/83)。 从初步研究结果显示, CA50值的测定对恶性肿瘤的诊断有一定的价值。

The Diagnostic Value of the Carbohydrate Antigen CA50 on the Malignant Tumors

The carbohydrate antigen CA50 was examined in serum level of 45 normal persons, 201 patients with benign diseases and 336 patients with malignannt tumor by immumoradiometric assay (IRMA). The results showed that the mean CA50 value in the patients with liver cancer,colon cancer and lung cancer was much higher then that in the nomal control group (P<0. 01). Taking 20 ku/L as the upper limit of nomal range, the positive rate were 79.1 % (53/67) of patients with liver cancer. 36. 4% (16/44) in colon cancer, 34. 9% (29/83) in lung cancer. From these results, we concluded that the measurement of level of serum CA50 may be an useful marker for malignant tumors diagnosis.