50例胃肠道平滑肌肿瘤临床病理研究

 本文报告50例胃肠道平滑肌肿瘤，胃部20例、十二指肠5例、空肠10例、回肠6例、结肠9例。良性29例、恶性21例。临床上本瘤诊断率低，当出现消化道出血、腹部肿块和腹痛时应高度怀疑本病。提出病理论断平滑肌肉瘤标准：1.瘤细胞核分裂≥1/10个高倍视野（HPF）、胃为3/10HPF.2.幼稚瘤细胞。3.瘤体直径大于7cm.4.瘤细胞对周围组织浸润。5.瘤细胞凝固性坏死。有第1项，有或无其他项；或后4项有其中两项即可考虑为平滑肌肉瘤，项目越多恶性程度越高。

Smooth muscle tumors of gastrointestinal tract——50 cases clinicopatholo}ic study

50 cases of smooth muscle tumor in gastrointestinal tract were analysed，including 20 cases in stomach，5 cases in duodenum, 10 cases in jejunum，6 cases in ileum and 9 cases in the large intes-tine. 29 cases belong to benign tumor and 21 cases leiomyosarcoma. The clinical diagnosis rate is lower to the gastroenteric leiomyoma, this disease must be thought in the patient who have abdomi-nal pain，almentary canal bleeding and abdominal mass. The authors suggest that (1) mitotic figures (≥1/10 HPF)，(2)cell anaplasia，(3)tumor size >7cm，(4)infiltration of tumor cell into the neigh-bouring tissue, (5) presence of necrosis may be considered as the criteria for diagnosis. The tumors possess the first item or two among the rest four item can be diagnosed the malignant smooth tu-mors of the gastrointestinal tract.