脑心通干预糖尿病患者心脑血管病疗效评估

目的:社区应用不同疗法治疗糖尿病患者,评估应用脑心通胶囊针对预防糖尿病心脑血管意外、实验室指标及干预颈动脉内层中膜厚度的临床疗效。方法:67例糖尿病患者分为2组予延续西药降糖、降脂等治疗。中药组应用脑心通胶囊治疗,对照组不应用中药汤剂或中成药治疗。持续治疗1年后从心脑血管不良事件、颈动脉彩超结果及血糖、血脂、糖化血红蛋白等生化指标等方面,评估其治疗效果。结果:与治疗前相比,中药组与对照组血脂较治疗前差异有统计学意义(P0.05),且2组间比较差异有统计学意义(P0.05)。中药组在IMT、血糖、糖化血红蛋白等指标方面治疗前后比较差异有统计学意义(P0.05),而对照组治疗前后比较差异无统计学意义(P0.05),2组比较差异有统计学意义(P0.05),中药组心脑血管不良事件较对照组少。结论:社区的糖尿病患者应用脑心通胶囊治疗有益于血糖、血脂控制,血管内皮保护及预防心脑血管不良事件。

Evaluation of Naoxintong Efficacy for Treating Cardiovascular Events in Diabetic Patients

Objective：To observe cardiovascular events,changes of laboratory parameters,and carotid internal media thickness in dia-betic patients applied with different treatment regimens.Methods：Sixty-seven patients were divided into 2 groups,both groups were trea-ted with western medicines,the Chinese medicine group was treated with Naoxintong in addition.After 1 years of continuous treatment, therapeutic effect was evaluated based on incidence of cardiovascular events,IMT,blood glucose and lipids,glycated hemoglobin and oth-er biochemical indicators.Results：There were significant blood lipid differences after treatment in both treatment groups （P 〈0.05）,and the difference was significant between 2 groups （P 〈0.05）.There was statistical significance before and after treatment in Chinese medi-cine group in IMT,blood glucose,glycosylated hemoglobin protein index （P 〈0.05）,while the control group before and after treatment had no significant difference （P 〉0.05）,there was significant difference between 2 groups （P 〈0.05）.The Chinese medicine group had less cardiovascular event incidence compared with the control group.Conclusion：Naoxintong has good effect for treating blood glucose and blood lipids which helps to prevent incidence of cardiovascular events in diabetic patients.