挖掘中医证候结构的方法学研究

从研究中医证候的发生规律入手,发现了中医证候内蕴的拓扑结构,形成了挖掘中医证候结构的拓扑学方法。这一方法学的优势体现在,可以实现中医证候信息完整保留基础上的分析运算,使证候结构拓扑分析结果的自然性与病机演变规律相吻合。运用拓扑学的方法,可以破解出中医证候的复杂结构,阐释中医证候判定标准的科学内涵,建立中医证候的判定诊断标准,形成"四特征五阶段"新辨证方法,并为探索中医证候的生物学基础提供理论依据;可以阐释中医理法方药精准对应的规律,建立中医辨证论治过程的可视化系统,形成辨证论治水平的评价体系;可以还原中医诊疗原型的基本结构,阐释中医诊疗原型系统,建立中医临床疗效评价体系。随着中医证候复杂结构的破解和释译,找到了中医证候理论的数学科学基础,使中医证候理论与现代科学有了对话与交流的结合点,有希望开启中医理论发展与临床实践的新时代。

Study on Methodology of Mining TCM Syndrome Structure

Starting from the occurring regularity of Traditional Chinese Medicine（TCM）syndrome,the topological structure of TCM syndromes was discovered and then the methodology of topology studying TCMsyndrome was formed.This methodology has the advantage of realizing the analysis and operation on the basis of information intact of TCMsyndrome,so as to achieve correspondence of the nature and disease evolution of topology analysis results.Topological methods can break out the complex structure of the scientific connotation of TCMsyndromes,build up the criteria of diagnosis of syndromes,form the new method of syndrome differentiation of the “four character-istics and five stages”,and provide a theoretical basis for the biological basis of syndromes;it can explain precisely corresponding rules of syndrome-principle-method-recipe -medicines;it can establish the system of visualization on the process of the treatment according to syndrome differentiation,forming the evaluating system of level of treatment according to syndrome differentiation;it can rebuild the basic structure of TCMdiagnosis and treatment,interprete the archetypes of TCMdiagnosis and treatment system,to establish the evalu-ation system of TCMclinical efficacy.With the crack and interpretation of complex structure of TCMsyndrome,finding the basis of the theory of TCMsyndrome of mathematical science and making the syndromes of TCMtheory and modern science are the combination of di-alogue and communication,and there is hope to open the new era of development of TCMtheory and clinical practice.