| 糖尿病加重中风的可能机制及相关药物作用靶点 |
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| 引用本文： | 李颖,于锋,戴德哉,戴茵.糖尿病加重中风的可能机制及相关药物作用靶点[J].药学进展,2010,34(10):433-438. |
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| 作者姓名： | 李颖 于锋 戴德哉 戴茵 |
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| 作者单位： | 中国药科大学药理研究室,江苏,南京,210009 |
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| 摘 要： | 糖尿病诱导脑神经损伤及脑血管病变，增加中风风险，导致预后不良，其病理过程可能涉及多种机制、多个靶点。综述有关糖尿病加重中风的可能机制及相关药物作用靶点的研究进展，为糖尿病合并中风的防治药物研发提供依据。
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| 关 键 词： | 糖尿病 中风 氧化应激 脑神经损伤 脑血管病变 |
Possible Mechanisms of Diabetes Aggravating Stroke and Therapeutic targets |
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| LI Ying,YU Feng,DAI De-zai,DAI Yin.Possible Mechanisms of Diabetes Aggravating Stroke and Therapeutic targets[J].Progress in Pharmaceutical Sciences,2010,34(10):433-438. |
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| Authors: | LI Ying YU Feng DAI De-zai DAI Yin |
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| Institution: | (Division of Pharmacology, China Pharmaceutical University, Nanfing 210009, China) |
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| Abstract: | Diabetes induces the cerebral nerve injury and cerebrovascular disease, increases the risk ot stroke and leads to the poor prognosis, which a variety of possible mechanisms and targets are involved in. The studies on the possible mechanisms of diabetes aggravating stroke and therapeutic targets were reviewed. It is beneficial to investigate new drugs for preventing diabetic patients from stroke. |
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| Keywords: | diabetes stroke oxidative stress cerebral nerve injury eerebrovaseular disease |
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